Projects in Progress
The project is focused on the use of natural biopolymers in a wide range of industries in the form of nanofibrous structures. Their added value is a significantly lower burden on the environment not only during their production, but also in other individual phases of the life cycle up to their biological breakdown and absorbability.
With this project, Nanoprogress joined the Employment Operational Program, which is supported by the European Union through the European Social Fund. The project is focued on solving problems with insufficient education of Nanoprogress members' employees. The main goal of the project is to enable the development of these employees thanks to education in various areas related to their work activities, which should help to increase their expertise and professional competences and, thanks to this, help the overall development of our members on the market and increase their competitiveness.Employees will be involved in the project in the form of training in the following areas:• General IT• Soft and managerial skills• Technical and other professional education• Accounting, economic and legal courses• Language education• Internal lecturerThe project is financed from the European Social Fund and the State Budget of the Czech Republic through the Employment Operational Program.
The overall goal of the project is to create a European strategic cluster partnership in the "Small Smart Green Cities" sector (GSSC ESCP-4i) and to expand the use of sustainable technological solutions from Europe to less developed areas of the world. This is planned to be achieved by promoting cross-border cooperation between clusters and internationalization support of European SMEs with first-rate solutions, complementary technologies and a collective vision to make a better world.
The project is focused on the development and implementation of fundamental innovations in AC spinning equipment for the preparation of polymer linear and planar composite nanostructures with regard to the processing of new materials and the preparation of new products, especially in the field of cosmetic and biomedical products, textile products, filtration and environmental technologies.
The project is focused on the application of highly innovative nanostructures in the brewing area. The main inention is the application of nanomaterials for the effective use of technological and waste water in order to achieve the target parameters and to strengthen the maintenance of the sensory and qualitative properties of the beer itself.
The project "Research of advanced nanostructures for applications in the field of food industry and water purification" is focused on the research and development of innovative nanofibrous structures and filter materials derived from them for applications in the field of filtration of food media and cleaning of contaminated wastewater and pool water. The goal of the project is: - Research, development and optimization of an innovative pilot-scale device that will enable the effective elimination of persistent, high-risk pesticide substances from waters. The effective elimination of pesticides will be based on the intensification of their contact with specific microbial consortia exhibiting increased capacity of biodegradation. For this purpose, the first device will be equipped with membranes based on hollow fibers, which will serve as a distributor of purified water. Hollow fibers will also be used as a support for biofilm structures formed by specific microbial consortia. The second device will use the latest findings from the field of nanomaterials research, specifically nanofibers prepared by spinning in an alternating electric field. Thanks to the use of nanofibers, increased contact of purified water/pesticides and specific biomass will be ensured. - The technology of a fully autonomous semi-operational filter device for the filtration of food media, especially wine, which will use, within this project, the developed filters based on nanofibers prepared through spinning in an alternating electric field (AC electrospinning) for filtration. - Research and development of the device that will enable folding of the developed flat AC nanofibrous membrane into a filter candle. - Development and optimizing of a modular device for the ultrafiltration of pool water using coiled candle prefilters and filters with nanofibrous structures. To achieve effective separation of the present microorganisms (bacteria, viruses, fungi, yeast, algae) and undissolved substances from the filtered pool water with the use of these filters. To demonstrate the functionality of the developed flat nanofibrous membrane and coiled candle filters with nanofibrous structures in the retention of unwanted substances and residues from filtered pool water and thereby achieve a reduction in the consumption of currently used disinfectants.
The goal of the project is the technological innovation and modernization of the existing research center of the Nanoprogress cluster through the acquisition of new equipment and the innovation of existing equipment. The project should expand the existing technological base of the Liberec establishment and improve the world's unique technology of nanofiber preparation (AC electrospinning).
In the years 2010 – 2013, the Nanoprogress cluster, in cooperation with a total of nine of its members and external companies, successfully prepared and implemented a national collective research project leading to the preparation and testing of innovative nanofibrous structures. The project was part of the Operational Entrepreneurship and Innovation Program within the Cooperation - clusters challenge I (the governing body OPPI - Ministry of Industry and Trade of the Czech Republic).
The main goal of this two-year implemented project was to improve the structure of the cluster, strengthen the membership base, improve the quality of management and other processes in order of gold label achievement for the cluster within the European initiative for cluster excellence, and thus to be included among the three percent of the best EU cluster organizations.
The main goals of the research, which is now in the implementation phase, are the optimization of the AC preparation of nanofibers, including coaxial ones, the preparation of flat nanostructures and composite membranes with specific properties, as well as the functionalization of these nanostructures by incorporating granular materials.
This project was implemented in the category of collective research and is divided according to its research focus into three sub-projects, which are described below. A number of small and medium-sized enterprises and research institutions participated in the implementation of the project. The project was successfully completed and the set goals were met in full.
The goal of the project was the preparation of functionalized nanosystems with controlled release of biologically active substances. The experimental work was focused on the optimization of the method for the preparation of microparticles for the treatment of connective tissue defects, the non-invasive treatment of skin tissue injuries and the characterization of the differentiation of mesenchymal stem cells in the developed nanostructures. Furthermore, polymer biomaterials were optimized, with use mainly as scaffolds for the proliferation and differentiation of mesenchymal stem cells for applications in regenerative medicine, which subsequently underwent in vitro testing successfully.
This project was implemented in the category of collective research and is divided into three sub-projects, which are described in more detail below. The implementation phase of all sub-projects of this project started in July 2015 and was completed in July 2018. A number of small and medium-sized enterprises and research institutions participated in the implementation of the project. All the set objectives of the project were met in full.
The project should expand the existing technological base of the Nanoprogress cluster and thus open new ways of the applicability of the world's unique nanofiber preparation technology using alternating current (AC electrospinning). It includes the supply of a functional model of equipment for the preparation and testing of flat and 3D structures and a functional model of equipment for the preparation of 3D nanofibrous structures from polymer and inorganic nanofibers. The goal of the project is to expand the technological base of the Nanoprogress cluster. The supplied devices should increase the application of nanofibrous structures, e.g. for the purposes of sorption of heavy metals, biomedical applications, applications in the field of inorganic nanofibers, applications in energetics, catalysis, biomedicine, and also expand their use in the range of 3D textiles and enable the improvement of standard products by adding a nanofibrous layer and creating a functionalized structure with added practical value. The newly acquired facilities will allow cluster members access to key technologies and, in addition to the possibility of expanding the product portfolio of industrial members, will allow the expansion of the knowledge base in the field of unique world knowledge obtained through research, design, construction and improvement of existing technology and their parts.
The Nanoprogress cluster has created and continuously continues to create, through implemented R&D projects focused on nanotechnology, a broad knowledge base in the field of preparation of nanofibrous structures, which can be followed up with another research project going to development of their own products based on nanofibrous structures and thus enabling their innovation needs to be fulfilled.
As part of this research project, analytical testing of the nanomaterial preparation process is carried out in terms of unwanted residues in individual phases and in the final structure, including the content of functionalizing additives (photocatalytic and magnetic). The goal is to optimize the production process in terms of quality and at the same time create reliable control procedures for evaluation. The output of the research will be necessary qualitative data usable for legislative approval processes in the given application area, which will enable more effective commercialization of specific future developed products.
The goal of the project is to implement a research program and create a knowledge base with pre-competitive nature of research outputs mainly in the following selected areas: - Via systematic research and development, to achieve a hybrid polymer membrane modified by nanomaterials, which will show long-term stable antimicrobial properties, and which will be applicable for effective filtration of biologically contaminated water - Implementation of membrane technologies in food technology, both in the conventional (must and wine filtration) as well as in the highly innovative technological part - Research and development of linear nanofibrous yarns with a minimum proportion of core yarn and a maximum proportion of nanofibrous component - Research and development of biotechnological and analytical methods and procedures leading to the efficient and sustainable acquisition of biomass with high potential for the isolation and production of biomedical substances - Study and testing of the therapeutic potential of nanofibrous scaffolds as carriers of selected types of human mesenchymal stem cells for the treatment of articular cartilage defects - Research and development of an injectable system based on functionalized nanofibers and a self-organizing gel with bioactive substances for laparoscopic operations in the therapeutic area of tissue defect regeneration - Study of the safety assessment and effectiveness of the surface and internal application of a covering material made of nanofibers functionalized with blood derivatives for its use in internal and external wound coverings and fixation materials for regenerative medicine - Research and development of biosensors based on second-generation nanofibers for the capture of specific molecules with the aim of using the huge surface of the nanostructure for the capture of molecules, both for non-specific capture and for specific capture by modifying the physico-chemical properties of the surface of the nanofibers or by modifying them with specific antibodies, withwhich the molecules react
The goal of the project is to implement this research program and create a knowledge base with pre-competitive character of research outputs in the following selected areas: - Identification of suitable input monomers and polymers containing substitution groups enabling the subsequent functionalization of spun polymers using chemical and biologically active substances - Synthesis of a polymer (polyurethane), which will contain suitable substitution groups for subsequent functionalization and at the same time, in terms of qualitative parameters, will be suitable for innovative applications in the field of biomedicine, food industry, remediation technologies and others - Improvement of specific physical and functional properties of nanofibrous structures - Development of procedures and selection of specific materials that will enable the production of laminates in such a way as to achieve the required mechanical properties, increase antimicrobial and antiallergic effectiveness and support their self-cleaning ability - Optimization of the mass representation of the nanofibrous layer, strength and productivity of linear nanofibrous composite or purely nanofibrous structures for certain input materials - Development of a combined medicinal product based on a nanofibrous carrier and endogenous material from stem cells atomized into the form of nanoparticles with therapeutic effectiveness
Value-Added Innovation in Nature Conservation Facilities (VIDA) will support and use the growth and innovation potential of SMEs operating within European food chains that link four complementary and interdependent sectors; of food, energy, water and key technologies (KET). VIDA will strengthen existing and create new cross-sectoral industrial value chains in the food and processing industries through a combination of direct and indirect innovation actions as well as support and capacity building measures.